Either Harvest or Rescue every Little Sister in the game.
Find every audio diary.
The player has taken a picture of Sander Cohen's corpse.
Acquire all upgrades for all weapons.
Fully upgrade five weapons.
Purchased every slot in all four Plasmid and Tonic tracks.
Successfully invent at least 100 items.
Complete the game without harvesting any Little Sisters.
The player has defeated Atlas.
The player has become a Big Daddy.
Fully upgrade four weapons.
Fully upgrade three weapons.
The player has broken Fontaine's mind control.
Fully upgrade two weapons.
The player has defeated Andrew Ryan.
Fully upgrade one weapon.
Purchased every slot in one of the Plasmid or Tonic tracks.
The player has completed Sander Cohen's great masterpiece.
Successfully invented all possible ammo types.
The player has restored the forests of Arcadia.
Shock an enemy in the water.
Successfully invent at least one item.
Successfully complete 50 hacks.
Acquire at least one weapon upgrade.
The player has defeated Peach Wilkins.
Take a Research Photo of the highest grade.
Purchase one slot in any Plasmid or Tonic track.
Take at least one Research Photo of a Splicer.
The player has defeated the crazed Dr. Steinman.
Successfully hack a safe.
Successfully hack a vending machine.
Successfully hack a turret.
Perform at least one successful hack.
Successfully hack a security bot.
Successfully complete the Welcome To Rapture Level.
Successfully hack a security camera.
Take at least one photo in every research group.
Fully research the Bouncer.
Fully research the Thuggish Splicer.
Fully research the Leadhead Splicer.
Fully research the Spider Splicer.
Fully research the Houdini Splicer.
Fully research the Nitro Splicer.
Fully research the Rosie.
Fully research the Little Sister.
Max out all possible research.
Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks.
Complete the game on the hardest difficulty setting.
Hit the jackpot at a slot machine.
The player has entered Sander Cohen's personal quarters.
Complete the game on Hard difficulty without using a Vita-Chamber.
Rescued the Little Sister in &The 'I' in Team&
Rescued the Little Sister in &The 'I' in Team& in under 3:00
Found all collectable Roses in &The 'I' in Team&
Rescued the Little Sister in &The 'I' in Team& without destroying any Machine Gun Turrets
Rescued the Little Sister in &A Shocking Turn of Events&
The player has rescued the Little Sister in &A Shocking Turn of Events& in under 4:00
Found all collectable Roses in &A Shocking Turn of Events&
Charged up the Ferris Wheel 9 different times in &A Shocking Turn of Events&
Rescued the Little Sister in &Worlds of Hurt&
Rescued the Little Sister in &Worlds of Hurt& in under 15:00, on Medium or higher difficulty
Found all collectable Roses in &Worlds of Hurt&
Rescued the Little Sister in &Worlds of Hurt& on medium or higher difficulty using only the wrench.
